PENGELOLAAN BERKELANJUTAN PERIKANAN DEMERSAL DI KAWASAN PULAU NUSA MANU DAN NUSA LEUN MALUKU TENGAH
نویسندگان
چکیده
منابع مشابه
Structural Basis for NusA Stabilized Transcriptional Pausing
Transcriptional pausing by RNA polymerases (RNAPs) is a key mechanism to regulate gene expression in all kingdoms of life and is a prerequisite for transcription termination. The essential bacterial transcription factor NusA stimulates both pausing and termination of transcription, thus playing a central role. Here, we report single-particle electron cryo-microscopy reconstructions of NusA boun...
متن کاملRNA-binding specificity of E. coli NusA
The RNA sequences boxA, boxB and boxC constitute the nut regions of phage lambda. They nucleate the formation of a termination-resistant RNA polymerase complex on the lambda chromosome. The complex includes E. coli proteins NusA, NusB, NusG and NusE, and the lambda N protein. A complex that includes the Nus proteins and other factors forms at the rrn leader. Whereas RNA-binding by NusB and NusE...
متن کاملStructure of a Mycobacterium tuberculosis NusA-RNA complex.
NusA is a key regulator of bacterial transcriptional elongation, pausing, termination and antitermination, yet relatively little is known about the molecular basis of its activity in these fundamental processes. In Mycobacterium tuberculosis, NusA has been shown to bind with high affinity and specificity to BoxB-BoxA-BoxC antitermination sequences within the leader region of the single ribosoma...
متن کاملN protein from lambdoid phages transforms NusA into an antiterminator by modulating NusA-RNA polymerase flap domain interactions
Interaction of the lambdoid phage N protein with the bacterial transcription elongation factor NusA is the key component in the process of transcription antitermination. A convex surface of E. coli NusA-NTD, located opposite to its RNA polymerase-binding domain (the β-flap domain), directly interacts with N in the antitermination complex. We hypothesized that this N-NusA interaction induces all...
متن کاملNascent RNA length dictates opposing effects of NusA on antitermination
The NusA protein is a universally conserved bacterial transcription elongation factor that binds RNA polymerase (RNAP). When functioning independently, NusA enhances intrinsic termination. Paradoxically, NusA stimulates the function of the N and Q antiterminator proteins of bacteriophage λ. The mechanistic basis for NusA's functional plasticity is poorly understood. Here we uncover an effect of...
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ژورنال
عنوان ژورنال: ALBACORE Jurnal Penelitian Perikanan Laut
سال: 2018
ISSN: 2655-559X,2549-1326
DOI: 10.29244/core.2.1.13-27